Preimplantation Genetic Testing (PGT)
What is Preimplantation Genetic Testing?
Preimplantation genetic testing helps in identifying defects of genetics in the embryos. PGT has become an integral part of Assisted Reproductive Technology. With this test, doctors diagnose if there is any genetic disease in the person. It helps to avoid the passing of any genetic condition to the child.
Only unaffected embryos are allowed to transfer for implantation in the uterus. It is to be remembered that negative PGT tests don’t guarantee that the newborn will take birth with zero birth defects.
Everything You Need to Know About Preimplantation Genetic Testing
Difference between PGD and PGS | Advantage PGD | Disadvantages PGD | PGS For Me | PGD and PGS Safe
Difference Between PGD And PGS
Preimplantation genetic diagnosis (PGD) helps to determine if the baby to be born of the embryo is also carrying the genetic abnormalities that are running in the family. It applies to situations where parents have a known genetic abnormality. If a family has a history of muscular dystrophy, sickle cell anemia, and cystic fibrosis, doctors recommend this test for them.
A PGD is done to check for a genetic condition in an embryo when it is known that both or one genetic parent has some genetic abnormality.
Whereas, Preimplantation genetic screening (PGS) applies to the couple with normal genes, but the embryo has a chromosomal abnormality. It is done to screen the embryo in order to check if there’s any genetic abnormality in an embryo before the transfer.
Preimplantation genetic testing involves the following steps:
It starts with the process of in vitro fertilization. In a laboratory, egg retrieval and fertilization will be done. The cell division of the embryos will start within the next three to five days. After this,
- The doctor removes a few cells from the embryo by laser biopsy and then freezes the embryos.
- After this, they evaluate the cells for determining the inheritance of a problematic gene in the embryo. It takes ten to twenty days.
- After the identification of genetic problems free embryo, the doctors will place it in the uterus.
- They freeze and keep the healthy embryos for the later pregnancy. It takes some weeks. It can take several weeks for getting the final results.
Sub Treatments For IVF
IVF/ICSI
ICSI-IVF is a procedure that includes both the procedures of IVF and ICSI. So, through ICSI, a single sperm is selected and is injected into the eggs for a healthy embryo.
Blastocyst Transfer
Blastocyst Transfer is the process of transferring an embryo that is in its last stage of development. In this stage, the embryo is of about 100-120 cells and is called a blastocyst.
Embryo Freezing
Embryo freezing helps to store embryos so that it can be used later. This is a much better and convenient option for couples who decide to store their embryo for using it later.
Embryo Transfer
Embryo Transfer is one of the last yet most important steps of an IVF procedure. It is a process of transferring an embryo into the uterus of a woman.
Sperm Freezing
Sperm freezing helps to resolve the infertility issue along with providing an option to have your own biological child in future.
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What are the Advantages of preimplantation genetic diagnosis?
There are some advantages of PGD which include the following.:
- With the test of PGD, doctors can detect hundreds of abnormal conditions of the gene. They can offer this to families with a history of single genetic defects which include sickle cell anemia, cystic fibrosis, and muscular dystrophy.
- The doctor performs this procedure before transferring and implanting the embryo and allows the couple to think about the pregnancy.
- It increases the chances of a healthy pregnancy by screening and diagnosing all kinds of genetic abnormalities.
What are the Disadvantages of PGD?
- PGD cannot remove the risk of conceiving a child with the genetic disorder completely, but it can only reduce the risk.
- With some genetic diseases, the carrier can develop the symptoms in their middle age. Then you need to discuss it with your doctor or physician.
Is PGS Right for me?
The doctors recommend this test for the parents who have no abnormalities in the gene. The other conditions are that the age of the woman needs to be thirty-eight years or more, the couple must be interested in transferring a single embryo and have a history of failed IVF or miscarriage or failed implementation. In such cases, the doctor may recommend PGS to you.
Is embryo biopsy, PGD, and PGS safe?
If you want to know about the safety of PGD, embryo biopsy, and PGS, the answer is yes. According to the result of PGD in animals and several human live births, PGD has no record of increasing birth defects. The alteration between the removal of trophectoderm cells of the early embryo and the development of the embryo’s ability into normal pregnancy is not possible.
You need to take or consult a genetic counsellor or doctor if you are considering testing PGD.
Patient Testimonials
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Abhishek Parashar
Hi, I and my wife Garima got married in 2013, and it's been 7.5 years since we had no children. We went to three-four doctors before visiting Gunjan IVF world. Then we went to Gunjan IVF center, where Doctor Gunjan ma’am guided us so friendly and she advised us to go for IVF. With their positive hands, we cracked in the first go and now we are blessed with twins. Especially, the team is too very cooperative they give you an environment which makes you feel very positive and comforting
Madhu Dhoundiyal
It's been an awesome journey with priceless outcome. My tubes were blocked and was trying to concieve from last 2 years and then I got to know about Gunjan IVF from outdoor branding. Finally I met Dr.Gunjan, for IVF treatment to concieve. I am lucky enough to get blessed with Twin Daughters, thank you Dr.Gunjan for everything.
Abhishek Parashar
Hi, I and my wife Garima got married in 2013, and it's been 7.5 years since we had no children. We went to three-four doctors before visiting Gunjan IVF world. Then we went to Gunjan IVF center, where Doctor Gunjan ma’am guided us so friendly and she advised us to go for IVF. With their positive hands, we cracked in the first go and now we are blessed with twins. Especially, the team is too very cooperative they give you an environment which makes you feel very positive and comforting
Madhu Dhoundiyal
It's been an awesome journey with priceless outcome. My tubes were blocked and was trying to concieve from last 2 years and then I got to know about Gunjan IVF from outdoor branding. Finally I met Dr.Gunjan, for IVF treatment to concieve. I am lucky enough to get blessed with Twin Daughters, thank you Dr.Gunjan for everything.
Our Expert Team
Dr. Gunjan Gupta Govil
Founder, Director & Gynaecologist with specialization in IVF, Infertility & Laparoscopy of 20+ years of experience.
(20+ years of experience)
Dr. Pradyot Kumar
Founder, CEO and a specialized Neurosurgeon who is an expert in complex Brain and Spine surgeries.
(25+ years of experience)
Mr. Gaurav Singhai
COO and an entrepreneur who co-founded Gujan IVF world along with Dr Gunjan and Dr Pradyot.
(5+ years of experience)
Paritosh Sarkar
Embryologist
He is a highly experienced and successful Embryologist with more than 10 years of experience in IVF.
(10+ years of experience)
Patient Guide
Along with treating our patients, we also guide them with the help of our educational blogs and videos.
Educational Blogs
Why do blastocyst not implant?
The reasons for an unsuccessful implantation are very uncommon and rare as well. Blastocyst provides a greater chance of becoming pregnant therefore the procedure is handled properly as well.
What happens after blastocyst transfer?
Before jumping to the immediate question first let’s have a small brief of what is blastocyst transfer. Blastocyst transfer is the transfer of embryos that have achieved a higher stage of development.
Can blastocyst fall out?
Maximum patients worry about what they can do or cannot do after an embryo transfer. They have the fear that if they do something wrong, the embryo would not attach or fall out.
Educational Videos
Difference between IUI, IVF and ICSI?
IUI stands for Intrauterine insemination or also known as artificial insemination. In this method, semen is washed and placed inside the uterine cavity so once the ovulation occurs or the egg is released the sperm will fertilise the egg.
IVF Process Start to Finish?
The couple has to undergo certain IVF treatment evaluations. These are the blood test before IVF. IVF tests for Females: The female has to undergo several tests such as female hormonal tests, egg count and quality assessment, blood tests such as AMH, prolactin, thyroid & basic tests such as hemoglobin, sugar, etc. ultrasound is done to check the uterus.
Best age to get pregnant?
Whether you want to conceive naturally or through IVF, the best period is between 20-30 years to get pregnant. During this time, women have the best fertility potential. Also, during this period the quantity and quality of the eggs or ovarian reserve is also good. As compared to men, increasing age affects women’s fertility a lot. If your age is between 25-30 years, the chances of getting pregnant with a single menstrual cycle are 25%. And as soon as your age increases, these pregnancy chances drop to just 5% when you reach 50.
Frequently Asked Questions
IUI Procedure step by step?
Do you know the success rate of pregnancy with the IUI procedures ranges from 15% to 20% per cycle? Yes, this is true. IUI, which is Intrauterine insemination, is a kind of artificial insemination that helps in treating infertility issues. This a quick process in which the pre-selected sperm is directly injected into your uterus or womb.
What happens after IUI day by day?
IUI or Intrauterine insemination is a less invasive procedure when compared to IVF or In vitro fertilization. Couples get many benefits from this procedure as the chances of pregnancy increase a lot because of IUI.
10 Ways Smoking kills Your Fertility?
Smoking comes as one of the most injurious habits to a person’s health and even when it comes to the fertility aspect, the impact is no different. This is where most of the fertility experts advise their clients to quit smoking whilst they are planning to have a child and it further lay a negative impact on the overall health of the future child in the process. Let’s see the 10 Ways Smoking kills Your Fertility.
Media Coverage
Most Trusted and Transparent IVF Center in Delhi NCR
Published on 29th Aug
The reasons for unsuccessful implantation are very uncommon and rare as well. Blastocyst provides a greater chance of becoming pregnant therefore the procedure is handled properly as well.
Best IVF Centre In U.P
The reasons for an unsuccessful implantation are very uncommon and rare as well. Blastocyst provides a greater chance of becoming pregnant therefore the procedure…
India Greatest Brand & Leaders Award
The reasons for an unsuccessful implantation are very uncommon and rare as well. Blastocyst provides a greater chance of becoming pregnant therefore the procedure…
Most Trusted and Transparent IVF Center in Delhi NCR
Published On: 29th Aug
The reasons for unsuccessful implantation are very uncommon and rare as well. Blastocyst provides a greater chance of becoming pregnant therefore the procedure is handled properly as well.
Best IVF Centre In U.P
Published On: 29th Aug