What is ovulation induction treatment?
Ovulation induction treatment is a straightforward fertility treatment. It has the involvement of injectable as well as oral medication, which stimulates regular ovulation. The medicines are taken at the initial stage of the menstrual cycle. The response of the body is further monitored with serial ultrasounds. The clinician sees your ovulation time and suggests the best time for either insemination ( See IUI step by step) or intercourse.
Ovulation induction indications
Many women may need ovulation induction as some of them infrequently ovulate, while others do not ovulate at all. These indications are most needed for an ovulation induction treatment.
While on the other hand, some women who ovulate regularly can also opt for this treatment to increase the number of eggs released per cycle. This will give them a better chance of conceiving. This treatment is also used by the patients when they undergo an IVF cycle. It helps them to maximize the production of an egg.
Medications Used for Ovulation Induction
The process of ovulation induction uses many hormone-based medicines so that the woman’s reproductive hormones are regulated. It also increases the chances of the release of mature eggs known as ovulation. Some of the drugs commonly used are:
- Clomiphene citrate
It helps to stimulate the ovaries for the development of eggs and ovulation in a woman who is not having changes in the hormones monthly. This medication is prescribed by your doctor.
- Aromatase inhibitors
This medicine proves to be outstanding for patients with PCOS. It is a very effective drug for inducing ovulation induction. Popularly known as letrozole.
- Insulin-sensitizing agents
PCOS patients who have evidence of prediabetics and diabetics use this medicine. This medication is known to be Metformin.
There are two hormones FSH and LH produced by the pituitary in the brain and they lead to the development of eggs in ovaries and subsequently ovulation. There are two injectable hormones, known as Follicle-stimulating hormone (FSH) and Human menopausal gonadotrophin( composed of both FSH + LH) which are used for ovulation induction.
The ovulation induction process
Step by Step Guide – ovulation induction
The ovaries get stimulated with the help of medicines. They promote the growth of follicles (egg sacs) that contains the eggs.
Serial Ultrasounds are known as follicular monitorings and blood tests help to monitor the response of the ovaries. These are beneficial to control the quantity and size of the follicles.
- Egg release
HCG or Human Chronic Gonadotropin injections are triggered to assist the egg when it is finally matured until the egg’s loosening from the follicles wall. Usually, a trigger is planned when the follicle or egg sacs reach the size of 18 to 20 mm as it helps in the final maturation and release of eggs or oocytes.
- Timed sexual intercourse or IUI
The couple is asked to perform intercourse tentatively around 36 hours post trigger injection. Doctors perform an ultrasound during the time of ovulation to see the follicles that are developed simultaneously released or not. It also helps determine the exact days to have sexual intercourse so that the chances of fertilization chances are maximized.
IUI helps to prepare the sample of sperms into the uterus directly. A fine tubing known as IUI cannula is inserted into the cervix or the uterus’s opening where the sperm that is adequately designed can be transferred gently ( see IUI step by Step ).
Risks associated with Ovulation Induction
Ovulation induction is a very straightforward and simple process but few and uncommon risks can be associated with the process. Risks that comes with ovulation induction are multiple pregnancies and Ovarian Hyperstimulation Syndrome (OHSS).
- Ovarian Hyperstimulation Syndrome or OHSS
This is an infrequent and, uncommon problem where the woman responds more to the induction process. This leads to the development of multiple follicles or egg sacs carrying multiple eggs. When such a woman gets an HCG trigger it leads to a hormone rush in the body. Due to that, symptoms like bloating, pain, vomiting, and nausea are widespread. But generally, they are easily overcome by simple medications as prescribed by the doctors. In extreme conditions, it can leads to fluid in the abdomen and lungs ( Ascites and Pleural Effusion) though this is very rarely encountered in the case of ovulation induction by drugs.
As days pass by, these risks are minimized by monitoring the cycle with ultrasound scans and blood tests.
- Multiple Pregnancy
Chances of multiple pregnancies are increased during ovulation induction due to multi follicular development. Chances are higher with Gonadotrophins ( 20%)followed by Clomiphene ( 10 %) and least with Letrozole( 5%).
Side effects of ovulation induction
Few side effects of ovulation induction are:
- Weight gain.
- Hot flashes
- Blurry visions
All these side effects are infrequent and are solved within a short time.
Benefits of ovulation induction
Ovulation induction is considered to be the first line of treatment that is used for infertility. This treatment gives you the benefits of non-invasive and low-cost treatment. Ovulation induction is also an effective treatment when conjunction happens between IUI, IVF, and other treatments.
Ovulation induction success rates
The success rate of ovulation induction depends upon the diagnosis of the woman and also some other factors. Some of the factors like age and medical history are all directly related to ovulation induction’s success rate. The success rate is 40% to 45% per cycle of pregnancy.
Ovulation induction Cost
The cost of ovulation induction treatment in India would be around Rs.2000 to Rs.10000 when being done with drugs or along with minimal gonadotrophins, depending on the gonadotrophin dosage required. It can reach from Rs 75, 000 to 1,00,000 in case of ovulation induction in IVF cases for Controlled Ovarian Hyperstimulation.
You can contact Dr Gunjan Gupta of Gunjan IVF World for a piece of better knowledge about the procedure. If you decide to go for this treatment, then we serve the best facilities for you.
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Rohit Krishna Gupta
Had a great experience with Dr. Gunjan. We visited the clinic as we had some queries regarding the conception process. Dr. Gunjan listened to the queries and answered all those with patience. And we had good news at the next consultation itself. Dr. Gunjan is very experienced, is soft-spoken, and very diligent with the process. Highly recommended!
Know the Expert before you visit our clinic
A team of Specialists working together as a team with a single Goal: Patient Satisfaction
Dr. Gunjan Gupta Govil
MRCOG(UK), MD(Gynae) – Founder & CEO
She is a Gynaecologist with specialization in IVF, Infertility & Laparoscopy specialist doctor and has close to 2 decades of experience in treating Infertility, performing Gynae Laparoscopy (Keyhole Surgeries) & Handing high-risk Pregnancies. She is a noted speaker in National and International level conferences and has also chaired various sessions on Infertility
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Dr. Pradyot Kumar
Dr. Pradyot Kumar is the founder and CEO of Gunjan IVF World. He is a Neurosurgeon with specialization
(20+ years of experience)
Mr. Gaurav Singhai
Co-Founder & COO
He has 15 years of Managerial Experience from various National & International Organizations like TCS, Fiserv & Sopra Steria. He has lived and worked with various MNCs in the US, UK, France & The Netherlands and gained immense experience and skills which he now contributes to Gunjan’s IVF World assiduously.
Dr. Abhishek Parihar
He is a dedicated & experienced Gynaecologist offering comprehensive fertility practice oriented towards fertility treatment. He has vast experience in dealing with infertile couples and providing health care assistance to them during course of their treatment.
He is a highly experienced and successful Embryologist with more than 10 years of experience in IVF. He has done M.Sc. in Biotechnology from MIMS, Jaipur. He has done more than 4000 IVFs and 3000+ ICSI cases till date.)
Dr. Arshi khan
She is another proud member of our medical team & while serving as a RMO for the past few years, she assists Dr. Gunjan during her session with various patients. Moreover, She is a graduate in BUMS and aspire to achieve greater heights in her career in the future.
Ms. Nivedita Rai
She is the Head Counselor at Gunjan IVF world who counsels and coordinates with our patients during the course of their treatment. Patients hold a very high regard for her. She has pursued her MBA from IMT Ghaziabad & been a part of our Gunjan IVF world Family since past many years.
We not just treat our patient, we also guide them throughout all medical terms and their problems
Do you know the success rate of pregnancy with the IUI procedures ranges from 15% to 20% per cycle? Yes, this is true. IUI, which is Intrauterine insemination, is a kind of artificial insemination that helps in treating infertility issues. This a quick process in which the pre-selected sperm is directly injected into your uterus or womb.
IUI or Intrauterine insemination is a less invasive procedure when compared to IVF or In vitro fertilization. Couples get many benefits from this procedure as the chances of pregnancy increase a lot because of IUI.
The reasons for an unsuccessful implantation are very uncommon and rare as well. Blastocyst provides a greater chance of becoming pregnant therefore the procedure is handled properly as well.
Before jumping to the immediate question first let’s have a small brief of what is blastocyst transfer. Blastocyst transfer is the transfer of embryos that have achieved a higher stage of development.
Normally in natural pregnancy, when a period cycle starts, an egg gets matured in the ovaries. When it becomes 18-20 mm then it is released at that time. After a physical relationship between a couple, the sperms fertilize this mature egg in the fallopian tube. Once the fertilization occurs, this fertilized egg converts into an embryo and sticks to the uterus that causes pregnancy.
If we talk about the term “Secondary Infertility” it generally refers to a situation when a woman is going through certain infertility issues even after carrying a baby already in her life. Moreover, this type of Infertility results in almost 50 percent of total infertility cases in women around the world. This is most common in couples who think of having a baby in their late 30s and 40s.
Egg freezing, medically known as human oocyte cryopreservation. It is an effective procedure allows the woman to go against the biological clock. It enables women to postpone pregnancy to a later date. In this phenomenon, eggs extracted, frozen and stored. The success rate of the procedure depends on the age of the woman and ranges from approximately 14% to 30%.