In vitro fertilization (IVF) is an assisted reproductive technology used by infertile couples. In this process of advanced reproduction, fertilization takes place outside the female body in a lab. Initially, the production of eggs is increased with hormonal injections, and doctors extract them once they become mature. Soon, they are mixed with the sperms, and fertilization occurs. At last, the formed embryo is transferred into the women’s uterus for implantation.

But sometimes, an embryo does not implant on the uterus wall, and pregnancy doesn’t occur. In this case, there could be some causes behind the failure of an IVF cycle.

Causes of failure of IVF

For successful implantation, the embryo should be of good quality. But sometimes, even good-quality embryos can fail to implant. A pregnancy and embryo development are like other biological processes. It is responsible for the failure of implantation in 90% of cases. These are as follows:

  • Embryo implantation rate– Embryo implantation rate is around 50% and 12% in the woman of age thirty-five and over forty respectively. If a woman has a poor quality embryo, it ends in not getting implanted. It results in a failed IVF because it stopped growing due to polyp or cysts in the ovaries.
  • The health of the uterus– Successful IVF procedure depends on the uterus health, woman’s age and the response of the body. Before an IVF procedure, doctors prescribe medication to stimulate the ovaries for the production of an egg. Some poor signs can include elevated FSH levels, a low number of eggs, and less body response towards IVF medications. The in vitro fertilization can be successful if your medication for IVF can produce more eggs. It is the indication of the normal functioning of hormones. In case it does not happen, it can reduce the chance of successful IVF.
  • Age and mental health of the woman– The age of a woman also affect the success of IVF. It is another reason for the failure of in vitro fertilization technique. The older woman who faces several failed IVF cycles end up trying for another one, and in return, the rate of success drops with every subsequent failure. Mental and emotional stress can also be responsible for IVF failure. If people stay in trauma or stress due to previously failed IVF, or some other reason, their mental health can cause pregnancy failure.

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Conclusion

Once the IVF procedure finishes, the implantation occurs after fourteen days. The embryo gets stuck to the uterus walls and starts dividing. In some cases, implantation doesn’t happen due to the problem of the uterus lining. The health of the uterine lining significantly impacts this procedure. The location of placing embryo, tube’s insertion and removal also hugely impact the success.

If you are facing failure in IVF treatment, do not give up. You need to reconsider the choice of doctor, the clinic and the services before attempting again. You need to stay positive and never give up.

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Dr. Gunjan Gupta Fertility and IVF Specialist in Delhi

Dr. Gunjan Gupta

Gynecologist and IVF specialist
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Dr. Gunjan Gupta is a Gynaecologist with a specialization in IVF, Infertility & Laparoscopy specialist doctor and has close to 2 decades of experience in : Treating Infertility, Performing Gynae Laparoscopy (Keyhole Surgeries) Handing high-risk Pregnancies. She is a Member of Royal College of Obs and Gynae (MRCOG) of UK and has been trained in Laparoscopy at EUDGES (France).

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