How to make IVF successful the first time?

An interesting article by IVF experts of the best IVF clinic in Delhi – Gunjan IVF World on how to achieve success in the first IVF attempt.

Couples undergoing or planning to go for IVF treatment always wish for achieve success in the first attempt of the treatment. It is important for them to know that maximising the chances requires them to take care of a lot of things. IVF experts of the best IVF clinic in Ghaziabad – Gunjan IVF World through this article attempts to create awareness on the parameter that need to be checked. Read the article to know what they could be.

What could be the factors of making IVF successful in the first time?

“Increasing the chances of a successful IVF cycle in the very first time calls for careful preparation, making the correct lifestyle choices, and working & adhering to the instructions of the IVF doctor. Though no one can guarantee success at the very first go because of factors like age and underlying health conditions of the couple but there are things that couples can do to increase their chances,” stated Dr. Gunjan Gupta, well-known gynaecologist Ghaziabad and the Medical Director & Founder of Gunjan IVF World – the best IVF clinic in Ghaziabad. Gunjan IVF World is the third time winner of North India’s best IVF clinic chain by ETHealthworld and has four highly advanced centres at Indirapuram, Janakpuri, Noida and Meerut.

Here are the factors that could possibly contribute to achieving success in the first IVF cycle

Choice of the clinic: “Always look for a clinic that has high live birth rates in your age group. Go for a clinic that gives you a baby and not just a positive beta-hCG. Make sure to enquire about the experience and expertise of the clinic and its doctors. Choose a clinic that has experience with your specific diagnosis like PCOS, male infertility, recurrent pregnancy loss, etc. A clinic with an advanced embryology lab is a must,” mentioned Dr. Gunjan Gupta.

Getting a full fertility workup done: “For a successful IVF treatment, it is important for couple to get a full fertility workup done. This will help the IVF doctors to analyse and plan for the right approach. The most common fertility workups suggested for women include a check of the ovarian reserve, i.e., AMH, FSH & antral follicle count and uterine health through ultrasound or hysteroscopy. In men, the workup usually involves semen analysis (check on sperm volume, count, motility & morphology) and DNA fragmentation test, if required,” said Dr. Garima Sharma, Centre In-Charge & Consultant at the best IVF center in Janakpuri – Gunjan IVF World.

Optimising health before the cycle: The following need to be taken care of before starting an IVF treatment to ensure successful outcomes. Women are required to ensure the below mentioned.

• Maintain a healthy BMI: Keep it 18.5-24.9 (higher or lower can impact success rates)
• Take prenatal vitamins with folic acid: Aim to take 400-800 mcg daily
• Manage conditions: PCOS, endometriosis, thyroid or insulin resistance
• Reduce alcohol & caffeine: Keep them <200mg caffeine/day
• Avoid smoking and recreational drugs

Men are advised to take care of the below mentioned.

• Avoid heat and tight clothes: Can affect sperm quality.
• Limit alcohol, avoid smoking and drug use
• Take male fertility supplements like CoQ10, zinc, vitamin C & E, folate

Managing stress: “It is a well-known fact that IVF treatment is usually emotionally draining. Chronic stress can impact the outcomes of the treatment. Things that we mostly recommend our patients to do to de-stress include yoga, meditation or therapy, trying acupuncture or joining support groups,” mentioned Dr. Meenakshi Arya, Centre In-Charge & Consultant of Gunjan IVF World, a leading IVF clinic in Meerut.

Follow the protocols exactly: It is necessary to take the medications on time. Injections like FSH, hCG trigger shots have to be done exactly as prescribed. Couples are advised to go for all monitoring appoints as that helps the doctor adjust dosages based on responses.

Consider advanced lab techniques if required:

• ICSI: For male infertility cases
• PGT-A: Can help in selecting chromosomally normal embryos (especially over age 35)
• Assisted hatching: Sometimes offered in certain cases to improve implantation

Support implantation: Doctors may schedule an embryo transfer based on the endometrial thickness and hormone levels of the woman. Make sure you’re compliant with your luteal phase support medications (e.g., progesterone injections or suppositories)

Lifestyle modifications during the two-week wait: Women are advised to continue with gentle activity but avoid high-impact workouts. They are recommended to wait for the blood test (beta-hCG) and not do continuous tests. Lastly, women are suggested to maintain a positive mindset but be prepared for any outcome.

Things that affect IVF success the most

• Age of the woman: most critical factor especially if the woman is over 35 years
• Embryo factor: High quality embryos implant better
• Uterine environment: Infections or abnormalities can hinder implantation
• Sperm quality: Even with ICSI, very poor quality can affect embryo development
• Lifestyle factors: Smoking, weight, alcohol and stress can impact success

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