Preimplantation Genetic Testing (PGT) in IVF

IVF experts of the best IVF center in Delhi – Gunjan IVF World share an informative article on PGT.

IVF is a complex treatment procedure involving many processes. Preimplantation Genetic Testing (PGT) is a technique in IVF that helps identify the genetic health of an embryo. Read this article by IVF experts of the best IVF clinic in Ghaziabad – Gunjan IVF World on what is PGT.

What is PGT?

“PGT or Preimplantation Genetic Testing is an IVF technique that involves analysis of the DNA of embryos that have been created through IVF. This test identifies the potential genetic or chromosomal anomalies before the embryo gets transferred into the uterus. There are commonly three types of PGT tests – PGTA (Preimplantation Genetic Testing for Aneuploidy) that detects abnormal chromosomal number, PGTM (Preimplantation Genetic Testing for Monogenic Disorders) which screens for specific inherited diseases and PGTSR (Preimplantation Genetic Testing for Structural Rearrangements) which detect chromosomal structural issues,” said Dr. Gunjan Gupta, renowned gynaecologist and Founder & Medical Director of Gunjan IVF World – North India’s best IVF clinic chain, three times in a row, by the Economic Times. Gunjan IVF World is the best IVF clinic in Ghaziabad with centres in Janakpuri, Noida and Meerut.

How is PGT done?

“The process of PGT starts with IVF and embryo creation, wherein eggs are fertilised with sperm in the IVF laboratory under controlled environment. The next stage involves the development of the embryo into the blastocyst stage, which is typically Day 5-6. This is followed by the biopsy stage where a few cells from the outer layer of each embryo are taken for genetic analysis. The DNA from these cells is tested in the lab. Based on the result, healthy embryos are identified and a chromosomally normal embryo is transferred to the uterus for implantation,” stated Dr. Garima Sharma, Consultant & Centre In-Charge of the best IVF center in Janakpuri – Gunjan IVF World.

What are the benefits of PGT?

“The benefits of Preimplantation Genetic Testing are many. It helps improve IVF success rates because it selects embryos that are more likely to implant. It reduces risks of miscarriage from chromosomal abnormalities and helps avoid genetic diseases if parents are carriers,” suggested Dr. Mayank Jain, IVF Consultant at Gunjan IVF World, Indirapuram.

Who should consider PGT?

PGT is mostly recommended to the following:

 Women over 35 years of age
 Couples with family history of genetic disorders
 Recurrent IVF failures or miscarriages
 Severe male infertility
 Carriers of chromosomal rearrangements

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