IVF-All you need to know about
Overview-what is IVF or In vitro fertilization
IVF is the most effective form of reproductive technology helps with fertilization, embryo development and implantation. It’s a series of complex procedures of insemination where an egg combined with sperm outside the body in a glass in a laboratory. Then, the fertilized eggs transferred to the uterus. A complete cycle of IVF takes around three weeks. It primarily aims to prevent genetic problems and assists with the conception of, child.
If you plan to conceive through IVF treatment, there are several stages which you need to undergo :
- Ovulation Induction: In the first phase, the doctor could prescribe medication for synthetic hormone generation to simulate the ovaries for producing multiple eggs. It has done so that one or more eggs may develop after fertilization. Possible medications include ovarian stimulation injections, medicines for oocyte maturation and progesterone supplements.
- Trigger Shot: Once the follicles ready, an injection is given to help eggs to mature completely and prepare them for fertilization. Within 36 hours of medication, eggs are ready for retrieval.
- Ovum Pick Up (OPU): In this, an ultrasound probe inserted into the vagina to identify follicles for retrieving eggs. The matured eggs then kept in nutritive liquid and incubated. Healthy eggs infused with sperm to create embryos.
- Sperm Collection: On the day of egg retrieval, a semen sample taken from your partner to separate sperms from the fluid in the laboratory.
- Fertilization (ICSI): This is the most important stage of the IVF cycle. Depending on the complexity, fertilization can be carried out through the insemination or ICSI method. In insemination, healthy sperm and matured eggs are mixed and incubated overnight. In the case of intracytoplasmic sperm injection, a single sperm injected directly into each matured egg. The latter was chosen in case of poor semen quality, low sperm count or repeated failures in fertilization attempts during previous IVF cycles.
- Embryo or Blastocyst Transfer: This three-day process is critical as some fertilized eggs transform into multi-celled embryos and further metamorphose into blastocysts. At this stage, they develop a fluid-filled cavity with tissues which ultimately separates into the placenta and baby.
Who are the right candidates
IVF procedure has proven to be a miracle for:
- Couples who have not been able to conceive even after trying for more than 6 months.
- People suffering from infertility problems including PCOS, endometriosis, tubal factor infertility, male factor infertility.
- People who want some kind of control over the genetics of the baby.
- Women who want pregnancy on demand.
What is the success rate
The success rate of IVF depends on certain factors including infertility cause, age factor and, where treatment’s done. According to research, depending on the age, the statistics claim that:
- Pregnancy achieved at an average of 29.4% of all cycles.
- IVF cycles that resulted in live births was on an average 22.4%
Cost cycle of IVF
An IVF treatment cycle is pretty much an expensive affair. The average cost for IVF ranges from Rs 70,000 to Rs 2,50,000. Besides, the medications vary according to the need
The risk associated with IVF procedure
There are several risks involved with IVF as discussed below:
- Multiple births: It may occur if more than one embryo implanted in the uterine wall.
- Pregnancy-induced Hypertension: Due to this procedure, mothers may suffer from high blood pressure.
- Need for C-section: Usually, C-section delivery done to avoid any risk.
- Preterm delivery and low birth weight: The probability of having a pre-term and weak baby are high with this procedure.
- Ovarian Hyperstimulation Syndrome: Swollen and painful ovaries due to side effects of IVF injections.
- Birth defects in the baby
- Risk of ovarian cancer
- Other problems include anemia, diarrhea, nausea, stress, hot flashes.