What is Mini or Micro IVF?
Mini-IVF is also called micro or minimal stimulation IVF. It follows the same pattern as in conventional IVF i.e. retrieval of the egg, fertilization of sperm and egg in simulated laboratory conditions finally followed by embryo transfer.
It differs from the conventional procedure in the amount of medication to be used for stimulating the ovaries for egg production. In mini- IVF smaller medication doses are used to produce few eggs. In many cases, no drugs are used for stimulating the ovaries.
Who Should Consider Mini-IVF?
Mini-IVF is a viable option in the following cases:
- If the woman has PCOS and is vulnerable to developing ovarian hyperstimulation syndrome (OHSS).
- If the woman has low ovarian or egg reserves. In such cases, more fertility drugs would have no impact on producing more eggs.
- If the woman has time constraints or is in a hurry. The treatment cycles in mini-IVF can happen back to back with no rest required.
- If the woman is about to undergo cancer treatment and wants to preserve her fertility. The fertility drugs used in conventional IVF might worsen cancer.
- If the woman has fear of needles. Mini- IVF employs far lesser injections.
Medications Taken During Mini-IVF
In conventional IVF, gonadotropins (Gonal-F, following, etc) are used to stimulate ovaries for egg production. For MINI-IVF, Clomid is generally used to stimulate the ovaries.
In some cases, small doses of gonadotropins may also be used to produce few eggs. Alternatively, mini- IVF can also be performed with no ovarian stimulating drugs. This, referred to as the natural cycle, is appropriate in cases of fallopian tube blockage or cases of male sterility. Apart from the stimulating drugs, GnRH antagonist drugs such as Anatagon and Cetrotide are required to prevent early or untimely ovulation.
Success Rates for Mini-IVF
The success rate for mini-IVF is generally lower than conventional IVF but mini- IVF has a better success rate than IUI ( Intrauterine insemination) with additional benefits.
Though the success rate is lower in comparison, mini- IVF benefits in the manner that it causes no ovarian hyperstimulation syndrome (OHSS). Hence, Mini-IVF is the preferred choice for women at risk of developing OHSS.
Mini-IVF After Failed Conventional IVF
Mini-IVF can be operational and work after failed conventional IVF.
The reason being mini- IVF is designed to produce fewer but quality eggs.
Conventional IVF can fail because of multiple factors which include: poor egg quality, stress, failed implantation, hormonal imbalances, etc. Thus, a lower stimulation technique such as mini-IVF can produce the desired effect as it can produce higher quality eggs.
Cost of Mini-IVF
The biggest advantage of Mini-IVF is the lower cost per cycle. The cost of a mini-IVF is generally 50 to 60 percent less than the conventional IVF.
However, mini-IVF costs more than IUI but still, the success rate of mini-IVF is greater than IUI.
The possible disadvantage of mini-IVF is that it is not viable if the number of eggs is needed. Also, if a cycle fails in mini-IVF, there will be no extra embryos for further cycles. We at Gunjan IVF provide the low cost ivf treatment in delhi ncr with a high success rates, because we know the joy of hearing mumma.
To sum up, even though the success rate of mini-IVF is low in comparison to conventional-IVF but looking at its low cost and lower risk of leading to ovarian hyperstimulation syndrome owing to optimized use of fertility drugs, it is a decent enough option for women.